Experimental biology and medicine epstein barr virus and human disease edited by p h levine d v ablashi m nonoyama g r pearson and. Epstein barr virus biology and disease the epstein barr virus ebv is a member of the herpesviridae virus family human beings are the primary reservoir for ebv. Epstein barr virus ebv is one of the most widespread human viruses with over 80 of the general population exposed by young adulthood as determined by antibody studies. Abstracts the epstein barr virus ebv is a well known example of a human virus which interacts most intimately with the immune system ebv is a polyclonal b lymphocyte activator can immortalize b cells and depending on situations can also induce different t cell and cytokine activities 1 6. Abstract since the discovery of epstein barr virus ebv from a cultured burkitts lymphoma cell line in 1964 the virus has been associated with burkitts lymphoma nasopharyngeal carcinoma and infectious mononucleosis
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