Paoletti e lipinskas br samsonoff c mercer s panicali d construction of live vaccines using genetically engineered poxviruses biological activity of vaccinia virus recombinants expressing the hepatitis b virus surface antigen and the herpes simplex virus glycoprotein d proc natl acad sci u s a 1984 jan 81 1193 197. Introduction the first published description of using a recombinant virus to deliver vaccine antigens from another infectious agent was the vaccinia virus recombinant engineered to express hepatitis b surface antigen in animal cells which upon immunization in chimpanzees induced protective immune response against hepatitis b . Bucher fremdsprachig wahlen sie die abteilung aus in der sie suchen mochten. Unknown author 1985 recombinant vaccinia viruses as live virus vectors for vaccine antigens memorandum from a who usphs nibsc meeting. Vaccinia virus vaccine vectors represent a promising potential as a safe effective vaccine platform we strive with competence and confidence to meet your demand for creating novel vaccines using vacv vectors and to promote vaccine development
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